Hepatitis

Available from www.who.in  
Accessed on 16/07/2014
Updated June 2014

Q: What is hepatitis?

A: Hepatitis is an inflammation of the liver. The condition can be self-limiting or can progress to fibrosis (scarring), cirrhosis or liver cancer. Hepatitis viruses are the most common cause of hepatitis in the world but other infections, toxic substances (e.g. alcohol, certain drugs), and autoimmune diseases can also cause hepatitis.

There are 5 main hepatitis viruses, referred to as types A, B, C, D and E. These 5 types are of greatest concern because of the burden of illness and death they cause and the potential for outbreaks and epidemic spread. In particular, types B and C lead to chronic disease in hundreds of millions of people and, together, are the most common cause of liver cirrhosis and cancer.

Hepatitis A and E are typically caused by ingestion of contaminated food or water. Hepatitis B, C and D usually occur as a result of parenteral contact with infected body fluids. Common modes of transmission for these viruses include receipt of contaminated blood or blood products, invasive medical procedures using contaminated equipment and for hepatitis B transmission from mother to baby at birth, from family member to child, and also by sexual contact.

Acute infection may occur with limited or no symptoms, or may include symptoms such as jaundice (yellowing of the skin and eyes), dark urine, extreme fatigue, nausea, vomiting and abdominal pain.

 

Hepatitis B

240 million people are chronically infected with hepatitis B virus.
Fact sheet on hepatitis B

 

Hepatitis C

150 million people are chronically infected with hepatitis C virus.
Fact sheet on hepatitis C

 

Hepatitis E

20% Hepatitis E can induce a mortality rate of 20% among pregnant women in their third trimester.
Fact sheet on hepatitis
 E

 

18 June 2014 -- Viral hepatitis – a group of infectious diseases known as hepatitis A, B, C, D, and E – affects millions of people worldwide, causing acute and chronic liver disease and killing close to 1.4 million people every year. Hepatitis remains largely ignored or unknown. In April this year, WHO issued new recommendations on treatment of hepatitis C. In May, World Health Assembly delegates from 194 Member States adopted a resolution to improve prevention, diagnosis, and treatment of viral hepatitis. On World Hepatitis Day, 28 July 2014, WHO and partners urge policy-makers, health workers and the public to "think again" about this silent killer.