Health policy Research Center

Pharmacoepidemiology & Pharmacoeconomics Group


About the Group

In 2012, Health Policy Research Center (HPRC) created Pharmacoepidemiology and Drug Safety Group to facilitate a wide range of activities related to the use and outcomes of drugs, addressed from a variety of interdisciplinary perspectives. The research program is directed at several pharmaceutical, epidemiological, therapeutic, and policy aspects of chronic drug use.  We follow-up on interesting and timely safety issues on an broad range of drugs, such as for example anti-viral and anti-neoplasm drugs, Antidiabetic drugs, lipid-lowering agents, antipsychotic drugs, or antihypertensive 

Our mission

The mission is to bring together the various specialties of Pharmaceutical Sciences, epidemiology, biostatistics, health services research, health policy and the social sciences to evaluate the effectiveness of existing and new prescription drugs in relation to their risks and safety; to study how drugs are used by physicians, patients and follow up by pharmacists; and to develop methods to optimize and utilized prescription drug use

Our vision

Our vision is to improve public health by enhancing the safety of marketed drugs through the development and application of Pharmacoepidemiology, drug safety and Pharmacovigilance research and to provide education on approaches to identify, assess, manage and minimize risk

Strategic Goals

Develop and assess new methods for population-based monitoring of drugs

Foster collaborations with public and private stakeholders, including academia, government, industry, advocacy and consulting groups, through a culture of cooperation and critical review

Provide graduate and continuing professional education on Pharmacoepidemiology and drug safety

Expand the pool of experts in Pharmacoepidemiology and drug safety research through the training of new researchers

Disseminate new approaches to drug safety and risk management to inform policy and practice

Research Interests

A Critical Evaluation of National and Local Pharma Data Record

Conducts observational research using large and medical databases data (electronic medical records)

 Population-based studies of drug treatment, drug prescription and pharmacoeconomy survey

Drug use in a population screening: Pharmacoepidemiological

Improving Pharmacovigilance and the Role of the Pharmacist

Epidemiology of drug exposure and adverse drug reactions

Evidence-based medicine/pharmacy

Prevention of medication errors and drug misuse/abuse

Pharmaceutical policy and administration

Clinical Trial

An introduction to Pharmacoepidemiology

Pharmacoepidemiology (drug epidemiology) is the study of the utilization and effects of drugs in large numbers of people; it provides an estimate of the probability of beneficial effects of a drug in a population and the probability of adverse effects. It can be called a bridge science spanning both clinical pharmacology and epidemiology. Pharmacoepidemiology concentrates on clinical patient outcomes from therapeutics by using methods of clinical epidemiology and applying them to understanding the determinants of beneficial and adverse drug effects, effects of genetic variation on drug effect, duration-response relationships, clinical effects of drug-drug interactions, and the effects of medication non-adherence. Pharmacovigilance is a part of Pharmacoepidemiology that involves continual monitoring, in a population, for unwanted effects and other safety concerns arising in drugs that are already on the market

Pharmacoepidemiology has come the development of concepts and methods to assess drug use. Although Pharmacoepidemiology is a relatively new term, research on drug use in epidemiology and public health has been ongoing for at least 4 decades. It is even possible to trace pharmacoepidemiological concepts back many centuries to Lind's "clinical trial'' using citrus fruit to treat scurvy, which was published in 1753, and studies by William Withering on the therapeutic effects of foxglove, published in 1785


Strom BL, Pharmacoepidemiology, latest edition

Strom BL, Text book of Pharmacoepidemiology, latest edition

Hartzema AG, Pharmacoepidemiology; An introduction, latest edition

Health policy Research Center
 71348-45794 :Postal code
Tel & Fax: + 98 71 3230 9615
Telegram: @HealthPolicyShiraz